5. A Commentary on George A. Scheele, M.D.
George A. Scheele, M.D.
December 15, 2015



In 1889 Johns Hopkins Hospital was established through a gift from Johns Hopkins and established under the leadership of Daniel Coit Gilman with four famous doctors, including William Henry Welch, William Osler, William Kelley and William Halsted.

About the time that Johns Hopkins Hospital was built, the germ theory had been developed in Europe by Pasteur, Lister, Cohn and Koch. Into that innovative world stepped Dr. Welch who made a life-long crusade to form Schools of Hygiene to improve world health. Through his leadership and the efforts of others, the Johns Hopkins School of Public Health was established and so was the Rockefeller Institute (now University) in New York.

In the aftermath of the discovery of penicillin by Alexander Fleming in 1928 the development of multiple families of antibiotics throughout the mid-20th century provided the tools for effectively treating infectious diseases.

Now more than 50 years later the most urgent need is to conquer the metabolic diseases that have reached epidemic proportions, not only in America but around the world. These diseases include overweight disorders, obesity, type-2 diabetes, lipid disorders, cardiovascular disease, inflammatory diseases, autoimmune disease, dementia, and Alzheimer’s Disease as well as mental disorders like depression, anxiety, chronic stress and sleep deprivation, which are all intertwined with a poorly understood condition known as the Metabolic Syndrome.


Dr. George Scheele, a collateral descendent from Johns Hopkins and a 1965 graduate of Johns Hopkins Medical School with a residency training on the prestigious Osler Medical Ward, has recently developed a basic and clinical science breakthrough in solving the crisis of chronic degenerative disease and aging by understanding that the common link between these divergent disorders operates through the appetite center in the brain stem, including the Arcuate Nucleus and the hypothalamus. Based on his recent discoveries of the role of essential amino acids in signaling satiety and health to the appetite center, he has developed Accelerated Amino Acid Delivery Technologies (AAADT) capable of effectively treating these diverse disorders and incorporated this technology in a health-care product called Factor4 Weight Control®.

The breakthrough utilized basic and clinical science and evolutionary biology to solve a number of health-care crises that afflict our modern society. Not only does it curtail (prevent, treat and cure) obesity but it also has beneficial effects on numerous chronic degenerative diseases associated with the metabolic syndrome. Dr. Scheele estimates that Factor4 products targeting these chronic degenerative diseases have the potential to reduce health-care costs from current levels of almost 18% of GDP to less than 10% of GDP within 10 years.

As President & CEO of NovaLife, Inc., Dr. Scheele has setup a Concierge Medical Service to treat metabolic disease with Factor4 Weight Control® and other line extensions to treat the chronic degenerative diseases listed above. Over the past 10 years Dr. Scheele has improved the health of more than 5,000 patients. The success of Dr. Scheele’s efforts in combatting chronic degenerative disease is no less than astonishing as demonstrated by articles posted on the Factor4 blogsite at

In order to continue his clinical research and fund the necessary clinical trials that are required for FDA approval of Factor4 products Dr. Scheele formed a 501c3 non-profit organization, the “Foundation to Improve World Health.” The nonprofit corporation has already applied the recent breakthroughs in clinical science to define the genetic and metabolic factors that lead to specific chronic degenerative disease and intends to conduct intensive educational and advocacy programs showing how innovative health-care strategies, like Factor4 Health products, can be used to improve metabolic health and lower health-care costs around the world.

Using the human genome, the human proteome, massive IT and systems biology the institute will further identify the specific metabolic proteins that are involved in the pathogenesis of each of these metabolic diseases. The Vision Statement, the Strategy Statement and the Operating Plan of the non-profit organization are available for review.


Dr. George Scheele is a direct descendant of the progenitors of the Snowden and Warfield families, which both arrived in Maryland in 1659. Throughout the 18th and 19th centuries they intermarried with the Thomas, Hopkins and Garret Families. The common denominator of these families was their commitment to medical work and their Quaker heritage, which spread across Colonial America in the early 19th century.

With extreme dedication to the needs of building a new Nation and the institutions that serve this nation these families and their descendants contributed greatly to society by founding a number of new institutions, including an impressive list of medical institutions, within four of the original 13 colonies, including Maryland, Pennsylvania, New Jersey and New York.

The family history website, established by Dr. Scheele, may be viewed at


The accomplishments of the Snowden and Warfield families and their descendants, which spans 4 centuries, are listed below:

  • Richard Snowden Sr., Jr. and The Youngest established the Patuxent Iron Works also known as the Snowden Iron Works in what would later become Laurel, MD.
  • Charles Alexander Warfield was the Hero of the Burning of the Peggy Stewart in the Annapolis Harbor in 1775, which decided the course that Maryland would pursue in the War of Independence. Charles Alexander was also the creator of the expression, “Give me Liberty and Independence or Death in Pursuit of it.”

Descendants of the Snowden and Warfield families were responsible for founding the following institutions in the mid-Atlantic region of what would become a new nation. The United States:

  • Charles Alexander Warfield was one of the Founders of the University of Maryland Medical School
  • Johns Hopkins both funded and founded the Johns Hopkins University, Hospital and Medical School in Baltimore, MD.
  • While John D. Rockefeller provided the funding, Simon Flexner, who was trained by William Henry Welch at Johns Hopkins, became the first Director of the Rockefeller Institute, now known as the Rockefeller University.
  • Simon’s brother, Abraham Flexner, founded the Rockefeller Foundation in New York City.
  • Abraham Flexner also founded, single-handedly, the Institute for Advanced Studies at Princeton. Later two prominent scientists would become Head of this Institute, Albert Einstein and J. Robert Oppenheimer.
  • Martha Carey Thomas who helped Mary Thomas Garrett provide the additional funds needed to open the Johns Hopkins School of Medicine, became the second President of Bryn Mawr College for Women in Bryn Mawr, Pennsylvania.
  • The Thomas and Garret families built the Baltimore and Ohio Railroad. Philip Even Thomas was the first of ten men who invested $25,000 in the B&O Railroad.
  • Philp Evan Thomas was also the first to contribute $25,000 to build the Washington Monument in Baltimore.
  • Richard Snowden, the Youngest, originally built Montpelier Mansion near the Patuxent River in Maryland. Today Montpelier Mansion is operated as a national historic site by the Maryland-National Capital Park and Planning Commission.

Now it is time for a direct descendant of both Richard Snowden and Richard Warfield to fund a non-profit Institute to Improve World Health through the prevention and treatment of metabolic disease here in America and throughout the world. Having worked with two Nobel Prize teams, awarded in 1974 and 1999, Dr. Scheele is infinitely qualified to lead in this effort.


The Scheele Family immigrated to the United States from Germany and Sweden in the early 19th Century. The best known member of the family in Europe was Carl Wilhelm Scheele, the Swedish Chemist who discovered oxygen, chlorine, barium and uric acid.

Carl W. Scheele, considered the greatest organic chemist of his time and possibly of all times, spent all of his professional years as a practicing apothecary. He was born in Stralsund, Sweden, into a family of German descent. Scheele was attracted to chemistry early in life and, at the age of 14, began an apprenticeship in Gothenburg in an apothecary shop.

Scheele’s fruitful investigations embraced inorganic, organic, and physical chemistry. Although Aristotle and Galen had speculated that air was an element and indivisible, Scheele determined in simple but ingenious experiments that air is composed of two gases, oxygen and nitrogen, in the approximate ratio of one to three, respectively. Oxygen was isolated during the ignition of red oxide of mercury, silver carbonate, magnesium nitrate, and potassium nitrate. The gas was recognized by him to be essential to respiration and in the germination of seeds.

In his discovery of uric acid, the initial observations were made on a collection of bladder calculi, which were pulverized and their properties studied with various physical and chemical agents. The previously unknown concrete or calculus acid was found in all urines and in higher concentrations in the sick than in the healthy.

George A Scheele, M.D.

Dr. Scheele is a world-renowned physician, inventor, author and two-time Nobel Associate, who has pioneered in understanding the critical role of amino acids in regulating metabolic health and body weight. He recently introduced Factor4 Weight Control® with essential ingredients to treat the four nutritional traps that lead to overweight disorders and obesity.

As a graduate of Princeton University and Johns Hopkins Medical School he served as Professors of Medicine on the faculties of The Rockefeller University, Yale University School of Medicine and Harvard Medical School. Dr. Scheele invented new concepts and techniques which “cracked the code” in understanding how Power Amino Acids® correct the deficiencies in amino acids, positive-charged proteins, and metabolic pathways that normalize body weight and restore metabolic health.

A pioneer in the development of the fields of Cell Biology and Molecular Biology and their impact on understanding chronic human diseases, he participated in work that won two Nobel Prizes in Medicine awarded in 1974 and 1999.

As a leader in nutritional science and medical research with 40 years of innovative scientific research and 10 years of breathtaking achievements in the fields of obesity and metabolic disease, Dr. Scheele’s passion has always been to “Make the World a Better Place”. After moving to La Jolla in 1998, he has utilized his vast experience to develop superior health-care products for individuals living in today’s fast-paced world.

Dr. Scheele is currently the Founder, President, and CEO of NovaLife, Inc. a San-Diego based biotech company that has pioneered in the development of innovative health-care products for people who suffer from obesity and metabolic diseases, including diabetes, lipid disorders, cardiovascular disease, autoimmune disorders, and aging.

Dr. Scheele is also the President of the Foundation and Institute to Improve World Health in La Jolla, CA.



William Henry Welch and the Heroic Age of American Medicine was originally written by Simon Flexner and published by Viking press in 1941. The publication was updated by James Thomas Flexner with the Johns Hopkins University Press in 1993.

Dr. Scheele has posted a series of 24 articles on the medical benefits and scientific principles underlying Factor4 Weight Control® success on his blogsite at These articles summarize the numerous medical and scientific breakthroughs in Factor4 Health based on Dr. Scheele’s innovative research over the past 45 years. These include:


The website for Improve World Health:

The Obesity Cure. George A. Scheele, 2011, Published by Bookmasters

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